The Lincoln University Hydroponic Research Program (HRP) was established in 2005 with the goal of increasing the productive capacity of the small-scale hydroponic industry, and limited resource farmers in Missouri, by providing grower education on profitable, but environmentally sustainable methods of hydroponic production. Projects designed to accomplish this goal utilize cost effective, simplified technologies and novel strategies for hydroponic crop culture that is consistent with the 1890 mission, while training future generations of horticultural scientists. Current research activities have distinctive focus. (1) Screening and evaluation of various vegetable crops, culinary/medicinal herbs and small fruits (blueberries and strawberries) in hydroponic systems for niche and specialty markets. (2) Investigate and develop sustainable nutrient management strategies for hydroponic production systems. In addition to sustainable food production, the HRP supports an innovative platform for education in agriculture, food safety, biology, and environmental sciences at Lincoln University of Missouri.