From St. Louis
Take I-70 W toward Kansas City. Take the US-54 exit, EXIT 148 and take US-54 W to Jefferson City. Merge onto US-63 S/ US-50 E/ Rex M Whitton Expy. Turn Right onto Jackson St and then Left onto Dunklin St. Turn Right onto Lafayette St and reach Lincoln University.
Take I-70 E toward St. Louis. Take the US-63 exit, EXIT 128A and take US-63 S to Jefferson City. Merge onto US-63 S/ US-50 E/ Rex M Whitton Expy. Turn Right onto Jackson St and then Left onto Dunklin St. Turn Right onto Lafayette St and reach Lincoln University.